Cancer Research: My goal is to produce
predictive models of the salvage
and de novo dNTP synthesis pathways for eventual applications in
rational optimizations of DNA targeted nucleoside analog cancer therapies. My current focus
is on ribonucleotide reductase (RNR). I am particularly interested in models wherein pre-equilibriums are represented
by total concentration constraint systems of polynomials in the free reactant concentrations, see
dTTP-induced R1 dimerization (2008). The slides (and abstract) of my most recent
talk (June 3rd, 2008) are available here.
R Software Development:
SBMLR is available from Bioconductor. Data packages can be found
here.
Teaching Interests:
Material from my Integrative Cancer Biology course of 2005 is
available.
May 2008 updates of some of these R scripts are available
here.
CV:
Here is my
CV.
Family:
Left to right are Schuyler, Tom, Carlton, Kirsten, Evan and Cody.
Website maintained by Tom Radivoyevitch .
