Radivoyevitch Lab

Cancer Research: My goal is to produce predictive models of the salvage and de novo dNTP synthesis pathways for eventual applications in rational optimizations of DNA targeted nucleoside analog cancer therapies. My current focus is on ribonucleotide reductase (RNR). I am particularly interested in models wherein pre-equilibriums are represented by total concentration constraint systems of polynomials in the free reactant concentrations, see dTTP-induced R1 dimerization (2008). The slides (and abstract) of my most recent talk (June 3rd, 2008) are available here.

R Software Development: SBMLR is available from Bioconductor. Data packages can be found here.

Teaching Interests: Material from my Integrative Cancer Biology course of 2005 is available. May 2008 updates of some of these R scripts are available here.

CV: Here is my CV.

Family: Left to right are Schuyler, Tom, Carlton, Kirsten, Evan and Cody.

Website maintained by Tom Radivoyevitch .