Dead-Band Control of HSC levels
v
Transplant doses of 10, 100, and 1000 CRU
=> CRU levels
1-20%
or 15-60% normal
Blood
(1996) 88: 2852-2858
v
Broad variation in human HSC levels
Stem Cells
(1995) 13: 512-516
v
Low levels of HSCs in BMT patients
Blood
(1998) 91: 1959-1965